SIFT¶

Description¶

SIFT predicts whether an amino acid substitution affects protein function. SIFT prediction is based on the degree of conservation of amino acid residues in sequence alignments derived from closely related sequences, collected through PSI-BLAST. SIFT can be applied to naturally occurring nonsynonymous polymorphisms or laboratory-induced missense mutations.

Environment Modules¶

Run module spider sift to find out what environment modules are available for this application.

Environment Variables¶

HPC_SIFT_DIR - installation directory
HPC_SIFT_BIN - executable directory

Categories¶

biology, genomics