Randfold¶

Description¶

Most non-coding RNAs are characterized by a specific secondary and tertiary structure that determines their function. Here, we investigate the folding energy of the secondary structure of non-coding RNA sequences, such as microRNA precursors, transfer RNAs and ribosomal RNAs in several eukaryotic taxa. Statistical biases are assessed by a randomization test, in which the predicted minimum free energy of folding is compared with values obtained for structures inferred from randomly shuffling the original sequences.

Environment Modules¶

Run module spider randfold to find out what environment modules are available for this application.

Environment Variables¶

HPC_RANDFOLD_DIR - installation directory
HPC_RANDFOLD_BIN - executable directory

Categories¶

biology, RNA