minimac¶

Description¶

Minimac3 is a lower memory and more computationally efficient implementation of the genotype imputation algorithms in minimac and minimac2. Minimac3 is designed to handle very large reference panels in a more computationally efficient way with no loss of accuracy. It accomplishes this by identifying repeat haplotype patterns and using these to simplify the underlying calculations, with no loss of accuracy.

Environment Modules¶

Run module spider minimac to find out what environment modules are available for this application.

Environment Variables¶

HPC_MINIMAC_DIR - installation directory
HPC_MINIMAC_BIN - executable directory

Citation¶

If you publish research that uses minimac you have to cite it as follows:

Fuchsberger C, Abecasis GR, Hinds DA. minimac2: faster genotype imputation. Bioinformatics 2014

Howie B, Fuchsberger C, Stephens M, Marchini J, and Abecasis GR. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing. Nature Genetics 2012.

Categories¶

biology, ngs