MHCflurry¶

Description¶

MHCflurry implements class I peptide/MHC binding affinity prediction. By default it supports 112 MHC alleles using ensembles of allele-specific models. Pan-allele predictors supporting virtually any MHC allele of known sequence are available for testing (see below). MHCflurry runs on Python 2.7 and 3.4+ using the keras neural network library. It exposes command-line and Python library interfaces.

Environment Modules¶

Run module spider mhcflurry to find out what environment modules are available for this application.

Environment Variables¶

HPC_MHCFLURRY_DIR - installation directory
HPC_MHCFLURRY_BIN - executable directory

Citation¶

If you publish research that uses mhcflurry you have to cite it as follows:

O’Donnell, T. J., Rubinsteyn, A., Bonsack, M., Riemer, A. B., Laserson, U., & Hammerbacher, J. (2018). MHCflurry: Open-source class I MHC binding affinity prediction. Cell Systems, 7(1), 129–132.e4. https://doi.org/10.1016/j.cels.2018.05.014

Categories¶

phylogenetics