Metabin

Description

metabin website

For comprehensive taxonomic binning, we developed the ‘MetaBin’ web server and standalone program for faster and more accurate taxonomic assignment of single and paired-end sequence reads of varying lengths (≥45 bp) obtained from both Sanger and next-generation sequencing platforms. We benchmarked it using both simulated reads (> 1 million) and real metagenomic datasets. MetaBin correctly assigns a higher number of reads to their expected taxonomic lineages with a lower error frequency as compared to other methods. It displays high accuracy (positive predictive value (PPV) ≥99%) along with high sensitivity (≥94%) for various read lengths. In particular, for short Illumina reads (~45-75 bp) it makes about 4% more assignments as compared to its closest competitors with near 100% accuracy when reference genomes are available.

Environment Modules

Run module spider metabin to find out what environment modules are available for this application.

Environment Variables

• HPC_METABIN_DIR - installation directory
• HPC_METABIN_BIN - executable directory

Categories

genomics