Meta-Tissue¶

Description¶

Meta-Tissue is a free software for identifying eQTLs from multiple tissues. It uses meta-analysis to combine results from multiple tissues. As the above picture shows, studies may not detect eQTLs in any of 4 tissues (cortex, heart, liver, spleen). However, by combining results of 4 tissues, we may detect eQTLs. Hence, Meta-Tissue is a powerful approach to detect eQTLs shared across multiple tissues.

Environment Modules¶

Run module spider meta-tissue to find out what environment modules are available for this application.

Environment Variables¶

HPC_META_TISSUE_DIR - installation directory
HPC_META_TISSUE_BIN - executable directory
HPC_META_TISSUE_EXE - examples directory

Citation¶

If you publish research that uses meta-tissue you have to cite it as follows:

Sul, J. H., Han, B., Ye, C., Choi, T., & Eskin, E. (2013). Effectively identifying eQTLs from multiple tissues by combining mixed model and meta-analytic approaches. PLoS Genetics, 9(6), e1003491. https://doi.org/10.1371/journal.pgen.1003491

Categories¶

biology, genomics