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homopolish

Description

homopolish website

Homopolish is a genome polisher originally developed for Nanopore and subsequently extended for PacBio CLR. It generates a high-quality genome (>Q50) for virus, bacteria, and fungus. Nanopore/PacBio systematic errors are corrected by retreiving homologs from closely-related genomes and polished by an SVM.

Modules system sets up the following environment variables for this module:

Environment Modules

Run module spider homopolish to find out what environment modules are available for this application.

Environment Variables

  • HPC_HOMOPOLISH_DIR - installation directory
  • HPC_HOMOPOLISH_BIN - executable directory

Citation

If you publish research that uses homopolish you have to cite it as follows:

Huang, YT., Liu, PY. & Shih, PW. Homopolish: a method for the removal of systematic errors in nanopore sequencing by homologous polishing. Genome Biol 22, 95 (2021). https://doi.org/10.1186/s13059-021-02282-6

Categories

biology